The Rams faced a fourth-and-7 at the Miami 48-yard line with 30 seconds left, and rather than go for a first down, coach Jeff Fisher sent out rookie Greg Zuerlein to try a 66-yard field goal, which missed wide left.
Zuerlein made two field goals to improve to 15 for 15 this season, but then missed three times in a row, including from 48 and 32 yards in the first half.
The Rams outgained the Dolphins 461 yards to 209.
Both teams are 3-3. Fisher lost to the team that courted him in January, when he chose the Rams job instead.