Kalil was injured in Carolina’s 16-12 loss to Seattle, although he continued playing.
Kalil went to see Dr. James Anderson on Tuesday and it was determined he had a Lisfranc injury, having torn a ligament that supports the middle of his foot.
He will have season-ending surgery on Monday and be placed on injured reserve.
A first-round draft pick by the Panthers in 2007, Kalil has been to the last three Pro Bowls and is a key cog in Carolina’s offense. Coach Ron Rivera says Geoff Hangartner will move from right guard to center and either Garry Williams or Jeff Byers will play right guard.
Source: Associated Press