Source: Chris Mortensen | ESPN 
The Indianapolis Colts were bracing for the worst after initial tests by doctors showed that receiver Reggie Wayne suffered a season-ending ACL injury in Sunday night’s victory over the Denver Broncos, according to league sources.
Colts doctors initially diagnosed torn ACL for Reggie Wayne; everyone hoping for a miracle as he goes into MRI on right knee.
— Chris Mortensen (@mortreport) October 21, 2013 
Colts fear WR Reggie Wayne tore his ACL, as @mortreport  reported. Will be an MRI to confirm if true.
— Adam Schefter (@AdamSchefter) October 21, 2013 
One source said it “looks like he’s out for the year” while another said the team was hoping the MRI “proves the doctors wrong on the ACL.”
Wayne is scheduled to undergo that MRI on Monday.
Colts owner Jim Irsay was hoping for the best through his Twitter account early Monday.
Prayers and much love for #87 Reggie…let's pray his right knee gets miracle news!!!!!! Love that man and pray for good news!!!!!!
— Jim Irsay (@JimIrsay) October 21, 2013 
As we speak, #Colts  WR Reggie Wayne is having an MRI, per source. The initial belief was serious knee injury, but should know for sure soon
— Ian Rapoport (@RapSheet) October 21, 2013