Source: Darin Gantt, Pro Football Talk 
The short version is, Spiller thinks he’s well enough to play, and Bills coach Doug Marrone thinks he might need a week off to get well.
Well, the official word for the week is in, and Spiller has been listed as doubtful on the injury report. According to Mike Rodak of ESPN.com, Marrone said Spiller would be a game-time decision.
CJ Spiller is doubtful. Game-time decision per Marrone
— Mike Rodak (@mikerodak) October 25, 2013